固有免疫应答、淋巴细胞激活、肿瘤免疫治疗

ORCID: 0000-0003-0956-3654

ResearcherID:

代表著作：

1. Matsumoto, R., Wang, D., Blonska, M., Li, H., Kobayashi, M., Pappu, B., ... & Lin, X. (2005). Phosphorylation of CARMA1 plays a critical role in T cell receptor-mediated NF-κB activation. Immunity, 23(6), 575-585.

2. Hsu, MY. , Zhang, Y.; You, Y.; Wang, D.; Li, H.; Duramad, O, Qin, X; Dong, C, Lin, X (2007) CARD9 is required for innate immune responses against intracellular pathogens. Nature Immunology, 8(2): 198-205.

3. Wu W, Hsu YM, Bi L, Songyang Z, Lin X. (2009) CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI- Rac1 complex. Nature Immunology. 10(11):1208-14.

4. Zhu LL, Zhao XQ, Jiang CY, You Y, Chen XP, Jiang YY, Jia XM, Lin X (2013) C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection. Immunity, 22; 39(2):324-34.

5. Zhao X, Guo Y, Jiang C, Chang Q, Zhang S, Luo T, Zhang B, Jia X, Hung MC, Dong C, Lin X (2017) JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression. Nat Med, 2017 Jan 23. doi: 10.1038/nm.4260.