今年Journal of Experimental Medicine(JEM)聚焦女性科学家,通过系列观点文章展示她们在学界做出的卓越贡献。近日,清华大学基础医学院、清华大学免疫学研究所朱可可研究员接受JEM采访,分享了她的科研经历以及作为独立研究者建立实验室的过程。
Journal of Experimental Medicine由洛克菲勒大学出版社出版,自从1896年创刊以来,JEM的目标一直是出版在医学生物学领域杰出且具有持久影响的研究。在医学生物学领域内,JEM既关注以人体为对象的研究,也关注各种体内实验模型对人类疾病的研究,包括但不限于遗传学、炎症、免疫、传染病、癌症、血管生物学、代谢紊乱、神经科学和干细胞生物学等方向。
该观点文章于2024年6月24日在JEM杂志‘Viewpoint’栏目在线发表,全文链接:https://doi.org/10.1084/jem.20240971。
采访内容如下
“My lab studies neuroimmune interactions in peripheral tissues, especially at mucosal barrier surfaces. I established my lab in August 2022. From my days as an undergraduate student, where I was exposed to science and learned how to develop experiments in the lab, which later became my PhD lab, I always had the goal of becoming a principal investigator (PI). The academic environment has always felt like a comfort zone to me—where people are friendly, ideas flow freely, and now, with the added joy of guiding and supporting the next generation of scientists. Somehow, alternative career paths never crossed my mind, at least not thus far. Of course, I encountered challenges and bottlenecks in my research endeavors. I would suggest: (1) having a hobby—for me, it’s playing ice hockey—which distracts you from the pressure; (2) don’t hesitate to seek help. You will find people are more willing to help than you might think. As for the right time to become independent, it has always been scary to leave the nest. However, once you have gained experience in securing grants, mentoring junior fellows, and crafting research proposals, I’m sure you are ready. So, take the leap. Everything will be okay. And when you look back, you’ll be very proud of yourself.”
(英译中由朱可可实验室博士生刘睿超完成)
我的实验室研究外周组织中的神经免疫相互作用,特别是关注黏膜屏障表面。在本科阶段,从我接触到科学研究并学会如何开展实验开始,我便树立了成为一名独立研究员(PI)的目标,而这里也正是我后来攻读博士学位所在的实验室。学术环境于我来说一直像是在舒适区——这里的人们都很友好,并且畅所欲言地交流学术观点,而现在又多了一份引导和支持下一代科学家的乐趣。不知为何,我从未考虑过其他职业道路,至少目前没有。当然,我在研究工作中也不可避免地遇到过挑战和瓶颈。对于此,我的建议是:(1)培养一个爱好,对我来说是打冰球,能帮助你从压力中解脱出来;(2)不要犹豫去寻求帮助,你会发现大家会比你想象中更愿意提供帮助。至于什么时候选择独立,诚然离开舒适区总会让人害怕。然而,一旦你在获得资助、指导年轻学者和制定研究计划等方面积累了一定经验,我相信你已经准备好了。所以,勇敢迈出这一步吧,一切都会好起来的。当你回首往事之时,你会为自己感到非常自豪。
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