Influenza in context: B cell responses to influenza inform on influenza vaccine development.

Dr. Patrick C. Wilson

The University of Chicago

Department of Medicine / Rheumatology

Knapp Center for Lupus and Immunology Research

Committee on Immunology

Abstract:

Dr. Wilson will discuss recent work in his laboratory concerning human B cell and antibody responses to influenza in various contexts such as during infection versus vaccination, responses to novel influenza vaccines in clinical trials, or responses to influenza vaccines or infection in different age groups ranging from the very young to the very old. Collectively this body of work provides important insights into how a universally protective influenza vaccine can be developed.

Introduction to Dr. Wilson:

Patrick C. Wilson, PhD, graduated from the University of Texas Southwestern Medical Center, Dallas, Texas where he trained with J. Donald Capra, MD and Virginia Pascual, MD. He received his postdoctoral training in the laboratory of Michel Nussenzweig, MD, PhD, at the Rockefeller University, NYC, NY. Patrick’s training was focused on B cell biology, antibody repertoire characterization, and the development of widely used approaches for generating recombinant monoclonal antibodies from single human B cells. Dr. Wilson’s laboratory studies B cell biology in the contexts of infectious diseases and immune tolerance, often using influenza vaccination or infection as an experimental model. His laboratory also has broad interests in influenza vaccinology including immune contexts affecting antibody and B cells responses to influenza, antibody epitope discovery, and the development of improved influenza vaccines or monolconal antibody-based therapeutics.

Time: 14:00 -15:30, August 27th (Tuesday)

Venue: Room D326, Medical Science Building

Host: Dr. Hai Qi